The Personification of Family - 799 Words

The Personification of Family â€Å"I have found the paradox, that if you love until it hurts, there can be no more hurt, only more love†. As humans we learn to accept those we love despite their strengths and weaknesses. We create bonds that go beyond logic and reasoning. Bonds that overpower the mind and with the proper time allow us to omit our pain. Love stands superior to all faults in a relationship. Such is the imperfection of love that without experiencing pain, love is never really understood. In Death of a Salesman, Arthur Miller presents Linda, the heart of the Loman family, as a mother figure that agrees with Mother Teresa’s quote. Linda is compassionate, understanding, and loving towards Willy, however she is seen as the family†¦show more content†¦Idolizing Ben, Willy too wants â€Å"to walk into the jungle† and become rich and with time learns to regret his decision, leaving Linda in regret. So with comfort she encourages him to believe in his illusions, in a way tha t caused her to retaliate in response to his failures. In addition when he starts realizing he’s a â€Å"pitiful adventurer of the road†, Linda makes excuses out of pity. Quick to jump to conclusions and make false accusations, Linda blames â€Å"the steering† and his â€Å"glasses† when Willy can’t seem to keep his mind on the road and returns home early from his business trip. â€Å"You didn’t rest your mind† Linda explains as Willy tries to remember what went wrong. His inevitable memories of his long ago affair with Miss Frances, allows Willy to admit â€Å"It’s me†. Feeling impotent Linda tells him to â€Å"just try to relax†. However, knowing that he is unable to work and borrows money from Charlie to provide for her, Linda can be described as â€Å"a blind leader of the blind†. Becoming aware of his ‘accidental’ crashes and the line attachment to the gas pipe, she is unable to explain re ality to him and creates a false world in which she ignores his suicidal attempts. However by not mentioning his stupidity she allows Willy to believe he is â€Å"†¦worth more dead than alive.† Without a doubt, however, Linda is an admirable wife. She is an amiable and sympathetic person who protects her husband from heartbreak and disappointment. And although her excessiveShow MoreRelatedPoetry and Schizophrenia726 Words   |  3 Pageslike similes, metaphors, personification, rhymes, and imagery to get their themes or meanings across to the reader. In the poem â€Å"Schizophrenia†, Jim Stevens uses personification of the house to give the poem its overall meaning. Personification and symbolism are the most important poetic elements to â€Å"Schizophrenia† because they are used to describe how the house can never be the same after the effects of schizophrenia and how the house personifies and symbolizes a family and the person with schizophreniaRead MoreAnalysis Of Sylvia Plaths Tulips831 Words   |  4 Pagesspeaker in the poem is in a hospital room, separate from their family. No one is present in the white hospital room, except for the speaker and the t ulips. The room is peaceful and allows the speaker to enjoy a lack of commitment towards anything. Unfortunately for the speaker, the tulips in the room remind the speaker of their life and bind the speaker to their responsibilities. In Sylvia Plath’s â€Å"Tulips,† color symbolism and personification contrast the peace of disconnection and commitments in lifeRead More Abandonment and Struggle on a Farm1327 Words   |  6 Pagesthe house and the family that lived in it through inanimate objects as well as the condition of the house and surrounding farmland. Using figurative language devices such as simile, metaphor, and personification Kooser allows the reader to draw their own conclusions. As well, Kooser allows the reader to fill in the gaps in his writing, however, he creates themes in this poem that are hard to ignore and thus they must be acknowledged. Themes of abandonment and a struggling family are prevalent in â€Å"AbandonedRead MoreAre You My Mother?993 Wo rds   |  4 Pagesend, the hatchling sees a crane and this crane miraculously led him back to the nest that he was born in. As he returns to the nest, his mother also comes back and introduces herself and finally reunite. In this book Dr. Eastman uses picture, personification, repetition and pathos, to illustrate that children, who grows up without their biological mother or father, seeks to know who their parents are and to allow parents know that their child would like to know them. In the beginning of the bookRead MoreEssay On Emily Dickinson1034 Words   |  5 Pageswho used her previously devastating personal experiences to enhance her poems. Emily Dickinson was born on December 10th, 1830 to Edward and Emily Dickinson in Amherst, Massachusetts. In the year 1833, her little sister Lavinia was born into the family. During February of 1852, A Valentine was published in the Springfield Republican. That was one of the first poems that she had written. Emily Dickinson was an amazing poet that wrote one thousand, eight hundred poems. Nine hundred of those poemsRead MoreAnalysis Of Ray Bradbury And Ursula Le Guin1385 Words   |  6 Pagesstrategies and modes contribute to the overall role of the protagonists. Ray Bradbury uses personification and the rhetorical mode of pathos to convey the oblivious suffering that the protagonist, the â€Å"smart house†, undergoes. Ursula Le Guin utilizes diction and the rhetorical mode of pathos to demonstrate the society’s dependency on the life of a young, hopeless boy. Through the authors’ use of diction, personification, and the rhetorical mode of pathos, readers can view both short stories in a new criticismRead MoreJohn Updikes Poem Ex-Basketball Player1225 Words   |  5 Pages(Preposition )to modern day gloom, he realistically develops the characterization of Flick. In his poem Ex-Basketball Player, John Updike uses personification along with allusions to improve characterization of Flick Webb and develop a somber tone of Flick Webb in his poem Ex-Basketball Player. In order to characterize Flick, Updike used personification to contrast Flick with his surroundings. In the poem, the speaker explains how Flick, the extraordinary basketball player,(Appositive) spends hisRead MoreThe Tragedy of Romeo and Juliet746 Words   |  3 Pagesbetween their two families. Their love is so strong that at the end of the story Romeo and Juliet both end up committing suicide because they can’t live without each other. Whether it is problems with love, or them complimenting each other on how they feel about the other person, Shakespeare uses many literary devices to make the reader dig deeper into the context to find the meaning behind the sentence. Some of the literary devices are; similes, metaphors, and personification. Shakespeare usesRead MoreThe Life Of Sylvia Path1212 Words   |  5 PagesMaster’s Degree in teaching and opted one of his father’s course†. â€Å"The grandparents of Otto wanted him to become a Lutheran minister and for the same reason he separated from them†. Three years later, her brother Warren was born. Afterward, her family had moved to Winthrop, Massachusetts in 1936. Most of Plath’s childhood was spent on Johnson Avenue. Eventually, her father, Otto Plath died on 5 November 1940 attending subtraction of the foot because of untreated diabetes. Her father fell sick soonRead MoreLiterary Elements In A Walk To The Jetty801 Words   |  4 Pagesprepared to leave her homeland and move onwards with her life by moving to England to become a nurse. As Annie was about to leave her resented homeland, she says, â€Å"‘I shall never see this again’ stabbed at me† (Kincaid 40). This is an example of personification because words cannot physically stab someone, but it could’ve meant that she felt some kind of mental discomfort after saying her piece of her mind. This shows that she’s afraid of going to leaving everything she knows behind in Antigua and start

Genetics Human Diseases

Question: Discuss about theGeneticsfor Human Diseases. Answer: Introduction The conditional gene knockout methodology would be used to address the learning and memory defects in the adult mouse. It is the process of inactivating the gene of interest in the specific tissue while in the wild type; the gene retains its original function. It is useful in studying the human diseases and developmental stages in human. In target gene inactivation, there is reliable association of the phenotype and the role of individual gene study in vivo. This conditional gene knockout methodology could be used to delete the Msc 1 gene in the brain tissue of the mouse and to study the learning and memory defects. The knockout mouse lacks the Msc 1 gene during the early embryonic stages and the learning and thinking defects are due to the developmental defects in the wiring of the brain. The conditional gene knockout creates the knockout mutations in embryonic stem cells and it is the best way by which the function and role of certain genes in human diseases are studied (Gierut, Jacks and Haigis 2014). The tissue- specific conditional knockout mouse is used to study the gene function and targeted validation. The targeted tissue in the brain associated with thinking or learning are inactivated that is there is no gene of interest and no expression and induced in the mouse (Davila et al. 2014). The same gene of interest is functional in the rest of the body. The knockout mouse would harbor a gene that completely lacks the normal function of the gene due to absence or non-functional gene product. The targeted gene deletion helps to study the biological role and the in vivo function of the specific gene in human diseases. The underlying pathophysiology is understood and the associated therapies in treating the disease. The Cre-Lox recombinase system is used to achieve the conditional knockout methodology. This method helps to knockout the gene of interest only in specific tissues. In conditional gene knockout, the DNA recombinase Cre and lox-P are the recognition sites (Kratochwil and Rijli 2014). In conditional, the target gene Msc 1 gene is modified by insertion of the lox-P in to the sites that excise the floxed gene segment by using Cre recombinase. The crossing of Cre transgenic with the floxed strain makes the inactivation of the target gene in vivo under the domain of Cre expression (Niesner and Maheshri 2013). The Msc 1 gene becomes inactivated in the Cre expressing cells while in other parts of the body the gene is active. References: Davila, D., Thibault, K., Fiacco, T.A. and Agulhon, C., 2014. Recent molecular approaches to understanding astrocyte function in vivo.Imaging and monitoring astrocytes in health and disease. Gierut, J.J., Jacks, T.E. and Haigis, K.M., 2014. Strategies to achieve conditional gene mutation in mice.Cold Spring Harbor Protocols,2014(4), pp.pdb-top069807. Kratochwil, C.F. and Rijli, F.M., 2014. The Cre/Lox system to assess the development of the mouse brain.Brain Development: Methods and Protocols, pp.295-313. Niesner, B. and Maheshri, N., 2013. Using the crelox system to randomize target gene expression states and generate diverse phenotypes.Biotechnology and bioengineering,110(10), pp.2677-2686.